Medical News: 24-Hour Monitoring Best to Diagnose Hypertension - in Cardiovascular, Hypertension from MedPage Today

Medical News: 24-Hour Monitoring Best to Diagnose Hypertension - in Cardiovascular, Hypertension from MedPage Today

Clinical Correlation in The Abdominal Examination

I've been posting about Abdominal Examination on last June, now I'll show you about some clinical correlation that we usually found in the abdominal examination. I hope this article will be worth,, ^___^

1. Abdominal Bruits. During Auscultation you listen to normal active bowel sound or some normal bruits (like bruits in the epigastric area from abdominal aorta, and the upper quadrants from renal arteries. But in some case you may listen to abnormal bruits. The abdominal bruits may be due to atherosclerotic lession, or masses that may be impinging on the abdominal aorta or renal arteries.
2. Rebound Tenderness. Begin palpating the abdomen very gently in all four quadrants. Look at the patient's face to see any signs of pain or discomfort. if there is abdominal tenderness, look for rebound tenderness by slowly pressing into the tender area then quickly releasing. Rebound tenderness may indicate peritonitis (inflammation of the peritoneum), which is classically seen in appendicitis.

Cardinal Sign of Acute Appendicitis

Cardinal sign of acute appendicitis:
- abdominal pain for less than 72 hours
- vomitting 1-3 times
- facial flush
- tenderness concentrated in the right iliac fossa
- rebound tenderness in the right iliac fossa
- anterior tenderness on rectal examination (9-11 positions)
- fever between 37,3 and 38,5 C
- no evidence of UTI on urine microscopy


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Renal Trauma Classification

Minor Renal Trauma (85%)


Grade I:

• Renal Contusion
• Sub capsular hematoma

Grade II:

• Ruptures/ tears of the renal capsule and parenchyma <1 cm
• Perirenal hematoma

Mayor Renal Trauma (15%)

Grade III:

• Parenchymal laceration > 1 cm into the cortex
• No urinary extravasation

Grade IV:

• Parenchymal laceration --> extend into the collecting system
• Urinary extravasation
• Laceration a segmental vessel

Grade V:

• Thrombosis of the main renal artery
• Multiple renal laceration --> Shattered kidney
• Avulsion of the main renal vessel

My sister's library floorplan

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Other Special Situations of Hypertension

Minorities

BP control rates vary in minority populations and are lowest in Mexican Americans and Native Americans. In general, the treatment of hypertension is similar for all demographic groups, but socioeconomic factors and lifestyle may be important barriers to BP control in some minority patients. The prevalence, severity, and impact of hypertension are increased in African Americans, who also demonstrate somewhat reduced BP responses to monotherapy with BBs, ACEIs, or ARBs compared to diuretics or CCBs.

These differential responses are largely eliminated by drug combinations that include adequate doses of a diuretic. ACEI-induced angioedema occurs 2–4 times more frequently in African American patients with hypertension than in other groups.

Obesity and the metabolic syndrome

Obesity (BMI >30 kg/m2) is an increasingly prevalent risk factor for the development of hypertension and CVD. The Adult Treatment Panel III guideline 17 for cholesterol management defines the metabolic syndrome as the presence of three or more of the following conditions: abdominal obesity (waist circumference >40 inches in men or >35 inches in women), glucose intolerance (fasting glucose >110 mg/dL), BP >130/85 mmHg, high triglycerides (>150 mg/dL), or low HDL (<40 mg/dL in men or <50 mg/dL in women).

Intensive lifestyle modification should be pursued in all individuals with the metabolic syndrome, and appropriate drug therapy should be instituted for each of its components as indicated.

Left ventricular hypertrophy

Left ventricular hypertrophy (LVH) is an independent risk factor that increasesthe risk of subsequent CVD. Regression of LVH occurs with aggressive BP management, including weight loss, sodium restriction, and treatment with all classes of antihypertensive agents except the direct vasodilators hydralazine, and minoxidil.

Peripheral arterial disease

Peripheral arterial disease (PAD) is equivalent in risk to IHD. Any class of antihypertensive drugs can be used in most PAD patients. Other risk factors should be managed aggressively, and aspirin should be used.

Hypertension in older persons

Hypertension occurs in more than two-thirds of individuals after age 65. This is also the population with the lowest rates of BP control. Treatment recommendations for older people with hypertension, including those who have isolated systolic hypertension, should follow the same principles outlined for the general care of hypertension. In many individuals, lower initial drug doses may be indicated to avoid symptoms; however, standard doses and multiple drugs

are needed in the majority of older people to reach appropriate BP targets.

Postural hypotension

A decrease in standing SBP >10 mmHg, when associated with dizziness or fainting, is more frequent in older patients with systolic hypertension, diabetes, and those taking diuretics, venodilators (e.g., nitrates, alpha-blockers, and sildenafillike drugs), and some psychotropic drugs. BP in these individuals should also be monitored in the upright position. Caution should be used to avoid volume depletion and excessively rapid dose titration of antihypertensive drugs.

Dementia

Dementia and cognitive impairment occur more commonly in people with hypertension. Reduced progression of cognitive impairment may occur with effective antihypertensive therapy.

Hypertension in women

Oral contraceptives may increase BP, and the risk of hypertension increases with duration of use. Women taking oral contraceptives should have their BP checked regularly. Development of hypertension is a reason to consider other forms of contraception. In contrast, menopausal hormone therapy does not raise BP.

Women with hypertension who become pregnant should be followed carefully because of increased risks to mother and fetus. Methyldopa, BBs, and vasodilators are preferred medications for the safety of the fetus. ACEI and ARBs should not be used during pregnancy because of the potential for fetal defects and should be avoided in women who are likely to become pregnant.

Preeclampsia, which occurs after the 20th week of pregnancy, is characterized by new-onset or worsening hypertension, albuminuria, and hyperuricemia, sometimes with coagulation abnormalities. In some patients, preeclampsia may develop into a hypertensive urgency or emergency and may require hospitalization, intensive monitoring, early fetal delivery, and parenteral antihypertensive and anticonvulsant therapy.

Hypertension in children and adolescents

In children and adolescents, hypertension is defined as BP that is, on repeated measurement, at the 95th percentile or greater adjusted for age, height, and gender. The fifth Korotkoff sound is used to define DBP. Clinicians should be alert to the possibility of identifiable causes of hypertension in younger children (i.e., kidney disease, coarctation of the aorta). Lifestyle interventions are strongly recommended, with pharmacologic therapy instituted for higher levels of BP or if there is insufficient response to lifestyle modifications.

Choices of antihypertensive drugs are similar in children and adults, but effective doses for children are often smaller and should be adjusted carefully. ACEIs and ARBs should not be used in pregnant or sexually active girls.

Uncomplicated hypertension should not be a reason to restrict children from participating in physical activities, particularly because long-term exercise may lower BP. Use of anabolic steroids should be strongly discouraged. Vigorous interventions also should be conducted for other existing modifiable risk factors (e.g., smoking).

Hypertensive urgencies and emergencies

Patients with marked BP elevations and acute target-organ damage (e.g., encephalopathy, myocardial infarction, unstable angina, pulmonary edema, eclampsia, stroke, head trauma, life-threatening arterial bleeding, or aortic dissection) require hospitalization and parenteral drug therapy. Patients with markedly elevated BP but without acute target organ damage usually do not require hospitalization, but they should receive immediate combination oral antihypertensive therapy. They should be carefully evaluated and monitored for hypertension-induced heart and kidney damage and for identifiable causes of hypertension.

Reference:

NIH Publication No. 03-5233

December 2003

Special Concideration of Hypertension: Cerebrovascular Disease

The risks and benefits of acute lowering of BP during an acute stroke are still unclear; control of BP at intermediate levels (approximately 160/100 mmHg) is appropriate until the condition has stabilized or improved. Recurrent stroke rates are lowered by the combination of an ACEI and thiazide-type diuretic.


Reference:
NIH Publication No. 03-5233
December 2003